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A Transgenic Insertional Inner Ear Mutation on Mouse Chromosome 1

OBJECTIVES/HYPOTHESIS: To clone and characterize the integration site of an insertional inner ear mutation, produced in one of fourteen transgenic mouse lines. The insertion of the transgene led to a mutation in a gene(s) necessary for normal development of the vestibular labyrinth. STUDY DESIGN: Mo...

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Detalles Bibliográficos
Main Authors: Friedman, Rick A., Adir, Yardit, Crenshaw, E. Bryan, Ryan, Allen F., Rosenfeld, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado: 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3897160/
https://ncbi.nlm.nih.gov/pubmed/10763993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/00005537-200004000-00001
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