Head Bobber: An Insertional Mutation Causes Inner Ear Defects, Hyperactive Circling, and Deafness

The head bobber transgenic mouse line, produced by pronuclear integration, exhibits repetitive head tilting, circling behavior, and severe hearing loss. Transmitted as an autosomal recessive trait, the homozygote has vestibular and cochlea inner ear defects. The space between the semicircular canals...

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Main Authors: Somma, Giuseppina, Alger, Heather M., McGuire, Ryan M., Kretlow, Jim D., Ruiz, Fernanda R., Yatsenko, Svetlana A., Stankiewicz, Pawel, Harrison, Wilbur, Funk, Etai, Bergamaschi, Antonio, Oghalai, John S., Mikos, Antonios G., Overbeek, Paul A., Pereira, Fred A.
Format: Artigo
Jezik:Inglês
Izdano: Springer-Verlag 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3346896/
https://ncbi.nlm.nih.gov/pubmed/22383091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-012-0316-5
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