Insertional Mutation on Mouse Chromosome 18 with Vestibular and Craniofacial Abnormalities

A dominant mutation was generated in transgenic mice as a consequence of insertional mutation. Heterozygous mice from transgenic line 9257 (Tg(9257)) are hyperactive with bidirectional circling behavior and have a distinctive facial appearance due to hypoplasia of the nasal bone. Morphological analy...

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Autores principales: Ting, C. N., Kohrman, D., Burgess, D. L., Boyle, A., Altschuler, R. A., Gholizadeh, G., Samuelson, L. C., Jang, W., Meisler, M. H.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1994
Materias:
Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1205776/
https://ncbi.nlm.nih.gov/pubmed/7511123
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