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Effect of abstinence challenge on brain function and cognition in smokers differs by COMT genotype

The val allele of the catechol-O-methyltransferase (COMT) val(158)met polymorphism has been linked with nicotine dependence and with cognitive performance in healthy volunteers. We tested the hypothesis that the val allele is a risk factor for altered brain function and cognition during nicotine abs...

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Bibliographische Detailangaben
Hauptverfasser: Loughead, J, Wileyto, EP, Valdez, JN, Sanborn, P, Tang, K, Strasser, AA, Ruparel, K, Ray, R, Gur, RC, Lerman, C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896978/
https://ncbi.nlm.nih.gov/pubmed/19065145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2008.132
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