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Association of abstinence-induced alterations in working memory function and COMT genotype in smokers

RATIONALE: The common val(158)met polymorphism in the catechol-O-methyltransferase (COMT) gene has been associated with nicotine dependence, alterations in executive cognitive function, and abstinence-induced working memory deficits in smokers. OBJECTIVES: We sought to replicate the association of t...

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Detalhes bibliográficos
Main Authors: Ashare, Rebecca L., Valdez, Jeffrey N., Ruparel, Kosha, Albelda, Benjamin, Hopson, Ryan D., Keefe, John R., Loughead, James, Lerman, Caryn
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3840089/
https://ncbi.nlm.nih.gov/pubmed/23828159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3197-3
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