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Adenosine A(1) receptors heterodimerize with β(1)-and β(2)-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling

G protein coupled receptors play crucial roles in mediating cellular responses to external stimuli, and increasing evidence suggests that they function as multiple units comprising homo/heterodimers and hetero-oligomers. Adenosine and β-adrenergic receptors are co-expressed in numerous tissues and m...

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Detalhes bibliográficos
Main Authors: Chandrasekera, P. Charukeshi, Wan, Tina C., Gizewski, Elizabeth T., Auchampach, John A., Lasley, Robert D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896953/
https://ncbi.nlm.nih.gov/pubmed/23291003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2012.12.022
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