Activated Pancreatic Stellate Cells Sequester CD8(+) T-Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma

BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is characterized by a prominent desmoplastic microenvironment that contains many different immune cells. Activated pancreatic stellate cells (PSCs) contribute to the desmoplasia. We investigated whether distinct stromal compartments are...

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Detalhes bibliográficos
Main Authors: Ene-Obong, Abasi, Clear, Andrew J., Watt, Jennifer, Wang, Jun, Fatah, Rewas, Riches, John C., Marshall, John F., Chin-Aleong, Joanne, Chelala, Claude, Gribben, John G., Ramsay, Alan G., Kocher, Hemant M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896919/
https://ncbi.nlm.nih.gov/pubmed/23891972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.07.025
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