FTO contributes to hepatic metabolism regulation through regulation of leptin action and STAT3 signalling in liver

BACKGROUND: The fat mass and obesity associated (FTO) gene is related to obesity and type 2 diabetes, but its function is still largely unknown. A link between leptin receptor-signal transducers and activators of transcription 3 (LepR-STAT3) signalling pathway and FTO was recently suggested in the h...

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Detalhes bibliográficos
Main Authors: Bravard, Amélie, Vial, Guillaume, Chauvin, Marie-Agnès, Rouillé, Yves, Bailleul, Bernard, Vidal, Hubert, Rieusset, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896784/
https://ncbi.nlm.nih.gov/pubmed/24410832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-12-4
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