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A bispecific antibody against two different epitopes on hepatitis B surface antigen has potent hepatitis B virus neutralizing activity

Treatment of chronic hepatitis B virus (HBV) infection with interferon and viral reverse transcriptase inhibitor regimens results in poor viral clearance, loss of response, and emergence of drug-resistant mutant virus strains. These problems continue to drive the development of new therapeutic appro...

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Detalhes bibliográficos
Main Authors: Tan, Wenlong, Meng, Yanchun, Li, Hui, Chen, Yang, Han, Siqi, Zeng, Jing, Huang, Ang, Li, Bohua, Zhang, Yanyun, Guo, Yajun
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896608/
https://ncbi.nlm.nih.gov/pubmed/24492346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.26390
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