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U1 small nuclear RNA chimeric ribozymes with substrate specificity for the Rev pre-mRNA of human immunodeficiency virus.

The in vivo effectiveness of ribozymes strongly depends on the correct choice of the vector molecule. High levels of expression, stability, active conformation, and correct cellular localization are the most important features for a ribozyme vector. We have exploited the utilization of the U1 small...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Principais autores: Michienzi, A, Prislei, S, Bozzoni, I
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1996
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38963/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7219
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