Doxorubicin Eliminates Myeloid-Derived Suppressor Cells and Enhances the Efficacy of Adoptive T Cell Transfer in Breast Cancer

Myeloid-derived suppressor cells (MDSC) expand in tumor-bearing hosts and play a central role in cancer immune evasion by inhibiting adaptive and innate immunity. They therefore represent a major obstacle for successful cancer immunotherapy. Different strategies have thus been explored to deplete an...

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Main Authors: Alizadeh, Darya, Trad, Malika, Hanke, Neale T., Larmonier, Claire B., Janikashvili, Nona, Bonnotte, Bernard, Katsanis, Emmanuel, Larmonier, Nicolas
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896092/
https://ncbi.nlm.nih.gov/pubmed/24197130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1545
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