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Micro-dystrophin and follistatin co-delivery restores muscle function in aged DMD model

Pharmacologic strategies have provided modest improvement in the devastating muscle-wasting disease, Duchenne muscular dystrophy (DMD). Pre-clinical gene therapy studies have shown promise in the mdx mouse model; however, studies conducted after disease onset fall short of fully correcting muscle st...

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Detalhes bibliográficos
Main Authors: Rodino-Klapac, Louise R., Janssen, Paul M. L., Shontz, Kimberly M., Canan, Benjamin, Montgomery, Chrystal L., Griffin, Danielle, Heller, Kristin, Schmelzer, Leah, Handy, Chalonda, Clark, K. Reed, Sahenk, Zarife, Mendell, Jerry R., Kaspar, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895965/
https://ncbi.nlm.nih.gov/pubmed/23863459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt342
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