Llwytho...

Smad3 is necessary for transforming growth factor-beta2 induced ocular hypertension in mice

TGFβ2 induces extracellular matrix (ECM) remodeling and alters the cytoskeleton by both the canonical Smad and non-canonical signaling pathways. TGFβ2 regulates the expression of ECM proteins in trabecular meshwork (TM) cells, increases intraocular pressure (IOP) in an ex vivo perfusion organ cultur...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: McDowell, Colleen M., Tebow, Holly E., Wordinger, Robert J., Clark, Abbot F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895953/
https://ncbi.nlm.nih.gov/pubmed/24184030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2013.10.017
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