The estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness

The role of the Forkhead box class O (FoxO)3a transcription factor in breast cancer migration and invasion is controversial. Here we show that FoxO3a overexpression decreases motility, invasiveness, and anchorage-independent growth in estrogen receptor α-positive (ERα+) cancer cells while eliciting...

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Detalhes bibliográficos
Main Authors: Sisci, Diego, Maris, Pamela, Cesario, Maria Grazia, Anselmo, Wanda, Coroniti, Roberta, Trombino, Giovanna Elvi, Romeo, Francesco, Ferraro, Aurora, Lanzino, Marilena, Aquila, Saveria, Maggiolini, Marcello, Mauro, Loredana, Morelli, Catia, Andò, Sebastiano
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3895429/
https://ncbi.nlm.nih.gov/pubmed/24047697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.26421
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