Akt2 Inhibition Enables the Forkhead Transcription Factor FoxO3a To Have a Repressive Role in Estrogen Receptor α Transcriptional Activity in Breast Cancer Cells

Estrogen receptor alpha (ER) and the insulin-like growth factor I receptor (IGF-IR) pathways are engaged in a functional cross talk in breast cancer, promoting tumor progression and increased resistance to anticancer treatments and radiotherapy. Here, we introduce new mechanisms through which protei...

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Autors principals: Morelli, Catia, Lanzino, Marilena, Garofalo, Cecilia, Maris, Pamela, Brunelli, Elvira, Casaburi, Ivan, Catalano, Stefania, Bruno, Rosalinda, Sisci, Diego, Andò, Sebastiano
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812247/
https://ncbi.nlm.nih.gov/pubmed/19933843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00824-09
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