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A Quinoxaline Derivative as a Potent Chemotherapeutic Agent, Alone or in Combination with Benznidazole, against Trypanosoma cruzi

BACKGROUND: Chagas’ disease is a condition caused by the protozoan Trypanosoma cruzi that affects millions of people, mainly in Latin America where it is considered endemic. The chemotherapy for Chagas disease remains a problem; the standard treatment currently relies on a single drug, benznidazole,...

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Hlavní autoři: Rodrigues, Jean Henrique da Silva, Ueda-Nakamura, Tânia, Corrêa, Arlene Gonçalves, Sangi, Diego Pereira, Nakamura, Celso Vataru
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894994/
https://ncbi.nlm.nih.gov/pubmed/24465654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085706
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