Expression and Functional Characterization of Membrane-Integrated Mammalian Corticotropin Releasing Factor Receptors 1 and 2 in Escherichia coli

Corticotropin-Releasing Factor Receptors (CRFRs) are class B1 G-protein-coupled receptors, which bind peptides of the corticotropin releasing factor family and are key mediators in the stress response. In order to dissect the receptors' binding specificity and enable structural studies, full-le...

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Detalhes bibliográficos
Main Authors: Jappelli, Roberto, Perrin, Marilyn H., Lewis, Kathy A., Vaughan, Joan M., Tzitzilonis, Christos, Rivier, Jean E., Vale, Wylie W., Riek, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894963/
https://ncbi.nlm.nih.gov/pubmed/24465390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084013
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