Possible Race and Gender Divergence in Association of Genetic Variations with Plasma von Willebrand Factor: A Study of ARIC and 1000 Genome Cohorts

The synthesis, secretion and clearance of von Willebrand factor (VWF) are regulated by genetic variations in coding and promoter regions of the VWF gene. We have previously identified 19 single nucleotide polymorphisms (SNPs), primarily in introns that are associated with VWF antigen levels in subje...

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Hlavní autoři: Zhou, Zhou, Yu, Fuli, Buchanan, Ashley, Fu, Yuanyuan, Campos, Marco, Wu, Kenneth K., Chambless, Lloyd E., Folsom, Aaron R., Boerwinkle, Eric, Dong, Jing-fei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894939/
https://ncbi.nlm.nih.gov/pubmed/24465435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084810
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