Possible Race and Gender Divergence in Association of Genetic Variations with Plasma von Willebrand Factor: A Study of ARIC and 1000 Genome Cohorts

The synthesis, secretion and clearance of von Willebrand factor (VWF) are regulated by genetic variations in coding and promoter regions of the VWF gene. We have previously identified 19 single nucleotide polymorphisms (SNPs), primarily in introns that are associated with VWF antigen levels in subje...

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Detalhes bibliográficos
Main Authors: Zhou, Zhou, Yu, Fuli, Buchanan, Ashley, Fu, Yuanyuan, Campos, Marco, Wu, Kenneth K., Chambless, Lloyd E., Folsom, Aaron R., Boerwinkle, Eric, Dong, Jing-fei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894939/
https://ncbi.nlm.nih.gov/pubmed/24465435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084810
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