Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort

von Willebrand factor (VWF) is an essential component of hemostasis and has been implicated in thrombosis. Multimer size and the amount of circulating VWF are known to impact hemostatic function. We associated 78 VWF single nucleotide polymorphisms (SNPs) and haplotypes constructed from those SNPs w...

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Detalhes bibliográficos
Main Authors: Campos, Marco, Sun, Wei, Yu, Fuli, Barbalic, Maja, Tang, Weihong, Chambless, Lloyd E., Wu, Kenneth K., Ballantyne, Christie, Folsom, Aaron R., Boerwinkle, Eric, Dong, Jing-fei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109544/
https://ncbi.nlm.nih.gov/pubmed/21343614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-08-300152
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