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Unfolded Protein Response Signaling and Metabolic Diseases
The endoplasmic reticulum (ER) is a central organelle for protein biosynthesis, folding, and traffic. Perturbations in ER homeostasis create a condition termed ER stress and lead to activation of the complex signaling cascade called the unfolded protein response (UPR). Recent studies have documented...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894306/ https://ncbi.nlm.nih.gov/pubmed/24324257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R113.534743 |
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