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Unfolded Protein Response Signaling and Metabolic Diseases

The endoplasmic reticulum (ER) is a central organelle for protein biosynthesis, folding, and traffic. Perturbations in ER homeostasis create a condition termed ER stress and lead to activation of the complex signaling cascade called the unfolded protein response (UPR). Recent studies have documented...

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Detalhes bibliográficos
Main Authors: Lee, Jaemin, Ozcan, Umut
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894306/
https://ncbi.nlm.nih.gov/pubmed/24324257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R113.534743
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