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Alphavirus Mutator Variants Present Host-Specific Defects and Attenuation in Mammalian and Insect Models
Arboviruses cycle through both vertebrates and invertebrates, which requires them to adapt to disparate hosts while maintaining genetic integrity during genome replication. To study the genetic mechanisms and determinants of these processes, we use chikungunya virus (CHIKV), a re-emerging human path...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3894214/ https://ncbi.nlm.nih.gov/pubmed/24453971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003877 |
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