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Modeling the estrogen receptor to growth factor receptor signaling switch in human breast cancer cells
Breast cancer cells develop resistance to endocrine therapies by shifting between estrogen receptor (ER)-regulated and growth factor receptor (GFR)-regulated survival signaling pathways. To study this switch, we propose a mathematical model of crosstalk between these pathways. The model explains why...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893882/ https://ncbi.nlm.nih.gov/pubmed/23994522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.08.022 |
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