Epidermal growth factor receptor signalling in human breast cancer cells operates parallel to estrogen receptor α signalling and results in tamoxifen insensitive proliferation

BACKGROUND: Tamoxifen resistance is a major problem in the treatment of estrogen receptor (ER) α -positive breast cancer patients. Although the mechanisms behind tamoxifen resistance are still not completely understood, clinical data suggests that increased expression of receptor tyrosine kinases is...

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Detalhes bibliográficos
Main Authors: Moerkens, Marja, Zhang, Yinghui, Wester, Lynn, van de Water, Bob, Meerman, John HN
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4021213/
https://ncbi.nlm.nih.gov/pubmed/24758408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-283
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