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Antigen-specific B lymphocytes acquire proteoglycan aggrecan from cartilage extracellular matrix resulting in antigen presentation and CD4(+) T-cell activation

The majority of studies examining antigen-presenting cell (APC) function have focused on the capture and presentation of antigens released from pathogens or damaged cells. However, antigen-specific B cells are also capable of efficiently extracting antigens that are either tethered to, or integrally...

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Detalhes bibliográficos
Main Authors: Ciechomska, Marzena, Wilson, Caroline L, Floudas, Achilleas, Hui, Wang, Rowan, Andrew D, van Eden, Willem, Robinson, John H, Knight, Andrew M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893851/
https://ncbi.nlm.nih.gov/pubmed/24032649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12169
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