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Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast.

The inhibition of DNA synthesis prevents mitotic entry through the action of the S phase checkpoint. In the yeast Saccharomyces cerevisiae, an essential protein kinase, Spk1/Mec2/Rad53/Sad1, controls the coupling of S phase to mitosis. In an attempt to identify genes that genetically interact with S...

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Bibliografiske detaljer
Main Authors: Sugimoto, K, Shimomura, T, Hashimoto, K, Araki, H, Sugino, A, Matsumoto, K
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC38933/
https://ncbi.nlm.nih.gov/pubmed/8692942
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