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Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast.

The inhibition of DNA synthesis prevents mitotic entry through the action of the S phase checkpoint. In the yeast Saccharomyces cerevisiae, an essential protein kinase, Spk1/Mec2/Rad53/Sad1, controls the coupling of S phase to mitosis. In an attempt to identify genes that genetically interact with S...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Sugimoto, K, Shimomura, T, Hashimoto, K, Araki, H, Sugino, A, Matsumoto, K
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38933/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692942/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7048
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