Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast.
The inhibition of DNA synthesis prevents mitotic entry through the action of the S phase checkpoint. In the yeast Saccharomyces cerevisiae, an essential protein kinase, Spk1/Mec2/Rad53/Sad1, controls the coupling of S phase to mitosis. In an attempt to identify genes that genetically interact with S...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692942/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.7048 |
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