Downregulation of PAX6 by shRNA Inhibits Proliferation and Cell Cycle Progression of Human Non-Small Cell Lung Cancer Cell Lines

BACKGROUND: The transcription factor PAX6 is primarily expressed in embryos. PAX6 is also expressed in several tumors and plays an oncogenic role. However, little is known about the role of PAX6 in lung cancer. METHODS: The function of PAX6 in lung cancer cells was evaluated by small interfering RNA...

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Main Authors: Zhao, Xiaoting, Yue, Wentao, Zhang, Lina, Ma, Li, Jia, Wenyun, Qian, Zhe, Zhang, Chunyan, Wang, Yue
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3893268/
https://ncbi.nlm.nih.gov/pubmed/24454925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085738
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