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Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase Cap-Snatching Domains
Orthomyxovirus Influenza A virus (IAV) heterotrimeric polymerase performs transcription of viral mRNAs by cap-snatching, which involves generation of capped primers by host pre-mRNA binding via the PB2 subunit cap-binding site and cleavage 10–13 nucleotides from the 5′ cap by the PA subunit endonucl...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3893164/ https://ncbi.nlm.nih.gov/pubmed/24454773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084973 |
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