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Insulin Receptors in the Liver: Specific Binding of [(125)I]Insulin to the Plasma Membrane and Its Relation to Insulin Bioactivity
With [(125)I]insulin at 7 × 10(-10) M, 25% of the radioactivity was bound to plasma membranes purified from rat liver. 20% of the [(125)I]insulin binding was inhibited by unlabeled insulin at 10(-9) M (6 ng/ml), equivalent to insulin concentrations in hepatic portal blood; inhibition of [(125)I]insu...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1971
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC389303/ https://ncbi.nlm.nih.gov/pubmed/4331561 |
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