Insulin Receptors in the Liver: Specific Binding of [(125)I]Insulin to the Plasma Membrane and Its Relation to Insulin Bioactivity
With [(125)I]insulin at 7 × 10(-10) M, 25% of the radioactivity was bound to plasma membranes purified from rat liver. 20% of the [(125)I]insulin binding was inhibited by unlabeled insulin at 10(-9) M (6 ng/ml), equivalent to insulin concentrations in hepatic portal blood; inhibition of [(125)I]insu...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1971
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389303/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4331561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.8.1833 |
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