Nalaganje...
IL-12 and type I interferon prolong the division of activated CD8 T cells by maintaining high-affinity IL-2 signaling in vivo
TCR ligation and co-stimulation induce cellular division; however, optimal accumulation of effector CD8 T cells requires direct inflammatory signaling by signal 3 cytokines, such as IL-12 or type I IFNs. Although in vitro studies suggest that IL-12/type I IFN may enhance T cell survival or early pro...
Shranjeno v:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2014
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3892973/ https://ncbi.nlm.nih.gov/pubmed/24367005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130901 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|