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Secondary CD8(+) T-cell responses are controlled by systemic inflammation

Repeated infections and experimental prime-boost regimens frequently result in the generation of secondary (2°) CD8(+) T-cell responses. In contrast to primary (1°) CD8(+) T cells, the parameters that influence the abundance and phenotype of 2° effector and memory CD8(+) T-cell populations are large...

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Detalhes bibliográficos
Main Authors: Wirth, Thomas C., Martin, Matthew D., Starbeck-Miller, Gabriel, Harty, John T., Badovinac, Vladimir P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083480/
https://ncbi.nlm.nih.gov/pubmed/21425157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040730
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