The Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses

Memory CD8 T cells provide protection to immune hosts by eliminating pathogen-infected cells during re-infection. While parameters influencing the generation of primary (1°) CD8 T cells are well established, the factors controlling the development of secondary (2°) CD8 T cell responses remain largel...

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Udgivet i:PLoS Pathog
Main Authors: Khan, Shaniya H., Martin, Matthew D., Starbeck-Miller, Gabriel R., Xue, Hai-Hui, Harty, John T., Badovinac, Vladimir P.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4592272/
https://ncbi.nlm.nih.gov/pubmed/26431533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005199
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