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Why tyrosine kinase inhibitor resistance is common in advanced gastrointestinal stromal tumors

Background: Most patients with advanced gastrointestinal stromal tumors (GIST) develop drug resistance to tyrosine kinase inhibitors (TKIs) within two years of starting therapy, whereas most chronic myeloid leukemia (CML) patients in chronic phase still exhibit disease control after a decade on ther...

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Bibliografski detalji
Glavni autori: Tomasetti, Cristian, Demetri, George D, Parmigiani, Giovanni
Format: Artigo
Jezik:Inglês
Izdano: F1000Research 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892920/
https://ncbi.nlm.nih.gov/pubmed/24555070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-152.v1
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