Gene Activation in WI-38 Fibroblasts Stimulated to Proliferate: Requirement for Protein Synthesis
Confluent monolayers of WI-38 human diploid fibroblasts can be stimulated to divide by fresh medium containing 30% fetal-calf serum. Up to 80% of the cells are stimulated to divide, with a peak of DNA synthesis between 15 and 21 hr. 1 hr after the change of medium there is a 70% rise in chromatin te...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1971
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389280/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5288757/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.8.1725 |
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