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Gene Activation in WI-38 Fibroblasts Stimulated to Proliferate: Requirement for Protein Synthesis

Confluent monolayers of WI-38 human diploid fibroblasts can be stimulated to divide by fresh medium containing 30% fetal-calf serum. Up to 80% of the cells are stimulated to divide, with a peak of DNA synthesis between 15 and 21 hr. 1 hr after the change of medium there is a 70% rise in chromatin te...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Rovera, Giovanni, Farber, John, Baserga, Renato
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1971
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389280/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5288757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.8.1725
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