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Gene Activation in WI-38 Fibroblasts Stimulated to Proliferate: Requirement for Protein Synthesis

Confluent monolayers of WI-38 human diploid fibroblasts can be stimulated to divide by fresh medium containing 30% fetal-calf serum. Up to 80% of the cells are stimulated to divide, with a peak of DNA synthesis between 15 and 21 hr. 1 hr after the change of medium there is a 70% rise in chromatin te...

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Detalhes bibliográficos
Main Authors: Rovera, Giovanni, Farber, John, Baserga, Renato
Formato: Artigo
Idioma:Inglês
Publicado em: 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC389280/
https://ncbi.nlm.nih.gov/pubmed/5288757
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