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Testing multiple biological mediators simultaneously

Motivation: Modern biomedical and epidemiological studies often measure hundreds or thousands of biomarkers, such as gene expression or metabolite levels. Although there is an extensive statistical literature on adjusting for ‘multiple comparisons’ when testing whether these biomarkers are directly...

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Detalhes bibliográficos
Main Authors: Boca, Simina M., Sinha, Rashmi, Cross, Amanda J., Moore, Steven C., Sampson, Joshua N.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892685/
https://ncbi.nlm.nih.gov/pubmed/24202540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt633
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