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FWER and FDR control when testing multiple mediators

MOTIVATION: The biological pathways linking exposures and disease risk are often poorly understood. To gain insight into these pathways, studies may try to identify biomarkers that mediate the exposure/disease relationship. Such studies often simultaneously test hundreds or thousands of biomarkers....

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Detalhes bibliográficos
Publicado no:Bioinformatics
Main Authors: Sampson, Joshua N, Boca, Simina M, Moore, Steven C, Heller, Ruth
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355102/
https://ncbi.nlm.nih.gov/pubmed/29420693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty064
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