ADAM17-mediated CD44 cleavage promotes orasphere formation or stemness and tumorigenesis in HNSCC

CD44, an extracellular matrix (ECM) receptor, has been described as a cancer stem cell marker in multiple cancers, including head and neck squamous cell carcinoma (HNSCC). HNSCC orasphere formation or stemness was characterized by cleavage of CD44, and thus we hypothesized that this proteolytic proc...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Kamarajan, Pachiyappan, Shin, Jae M, Qian, Xu, Matte, Bibiana, Zhu, Joey Yizhou, Kapila, Yvonne L
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2013
Teme:
Cancer Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892384/
https://ncbi.nlm.nih.gov/pubmed/24403253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.147
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki