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NMR structural analysis of Sleeping Beauty transposase binding to DNA

The Sleeping Beauty (SB) transposon is the most widely used DNA transposon in genetic applications and is the only DNA transposon thus far in clinical trials for human gene therapy. In the absence of atomic level structural information, the development of SB transposon relied primarily on the bioche...

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Bibliografiska uppgifter
Huvudupphovsmän: E Carpentier, Claire, Schreifels, Jeffrey M, Aronovich, Elena L, Carlson, Daniel F, Hackett, Perry B, Nesmelova, Irina V
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892296/
https://ncbi.nlm.nih.gov/pubmed/24243759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2386
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