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NMR structural analysis of Sleeping Beauty transposase binding to DNA

The Sleeping Beauty (SB) transposon is the most widely used DNA transposon in genetic applications and is the only DNA transposon thus far in clinical trials for human gene therapy. In the absence of atomic level structural information, the development of SB transposon relied primarily on the bioche...

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Autors principals: E Carpentier, Claire, Schreifels, Jeffrey M, Aronovich, Elena L, Carlson, Daniel F, Hackett, Perry B, Nesmelova, Irina V
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892296/
https://ncbi.nlm.nih.gov/pubmed/24243759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2386
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