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Molecular and Clinical Investigation of Iranian Patients with Friedreich Ataxia

Background: Friedreich ataxia (FRDA) is an autosomal recessive disorder caused by guanine-adenine-adenine (GAA) triplet expansions in the FXN gene. Its product, frataxin, which severely reduces in FRDA patients, leads to oxidative damage in mitochondria. The purpose of this study was to evaluate the...

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Bibliografiske detaljer
Main Authors: Salehi, Mohammad Hossein, Houshmand, Massoud, Aryani, Omid, Kamalidehghan, Behnam, Khalili, Elham
Format: Artigo
Sprog:Inglês
Udgivet: Pasteur Institute of Iran 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892137/
https://ncbi.nlm.nih.gov/pubmed/24375160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6091/ibj.1235.2013
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