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Molecular and Clinical Investigation of Iranian Patients with Friedreich Ataxia

Background: Friedreich ataxia (FRDA) is an autosomal recessive disorder caused by guanine-adenine-adenine (GAA) triplet expansions in the FXN gene. Its product, frataxin, which severely reduces in FRDA patients, leads to oxidative damage in mitochondria. The purpose of this study was to evaluate the...

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מידע ביבליוגרפי
Main Authors: Salehi, Mohammad Hossein, Houshmand, Massoud, Aryani, Omid, Kamalidehghan, Behnam, Khalili, Elham
פורמט: Artigo
שפה:Inglês
יצא לאור: Pasteur Institute of Iran 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892137/
https://ncbi.nlm.nih.gov/pubmed/24375160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6091/ibj.1235.2013
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