SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease

BACKGROUND: Multiple sclerosis (MS) is characterized by central nervous system inflammation and demyelination, and increasing evidence demonstrates significant neuronal damage also occurs and is associated with permanent functional impairment. Current MS therapies have limited ability to prevent neu...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Khan, Reas S, Dine, Kimberly, Das Sarma, Jayasri, Shindler, Kenneth S
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892130/
https://ncbi.nlm.nih.gov/pubmed/24383546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-3
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