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SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease

BACKGROUND: Multiple sclerosis (MS) is characterized by central nervous system inflammation and demyelination, and increasing evidence demonstrates significant neuronal damage also occurs and is associated with permanent functional impairment. Current MS therapies have limited ability to prevent neu...

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Detalhes bibliográficos
Main Authors: Khan, Reas S, Dine, Kimberly, Das Sarma, Jayasri, Shindler, Kenneth S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892130/
https://ncbi.nlm.nih.gov/pubmed/24383546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-3
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