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SIRT1 Promotes RGC Survival and Delays Loss of Function Following Optic Nerve Crush
PURPOSE. Activation of SIRT1 deacetylase prevents retinal ganglion cell (RGC) loss in experimental optic neuritis, an inflammatory optic neuropathy. While mechanisms of this effect are not known, evidence suggests it involves reduction of oxidative stress. We hypothesized that SIRT1 reduces RGC loss...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726244/ https://ncbi.nlm.nih.gov/pubmed/23821198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12157 |
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