The mTOR signaling pathway regulates pain-related synaptic plasticity in rat entorhinal-hippocampal pathways

BACKGROUND: Our previous work demonstrated that persistent peripheral nociception (PPN) leads to synaptic plasticity and functional changes in the rat hippocampus. The protein kinase mTOR is a critical regulator of protein synthesis-dependent synaptic plasticity in the hippocampus as well as synapti...

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Autors principals: Lyu, Dan, Yu, Wenli, Tang, Ning, Wang, Ruirui, Zhao, Zhenyu, Xie, Fang, He, Yongjin, Du, Hongyin, Chen, Jun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892125/
https://ncbi.nlm.nih.gov/pubmed/24313960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-9-64
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