Neuronal Expression of GalNAc Transferase Is Sufficient to Prevent the Age-Related Neurodegenerative Phenotype of Complex Ganglioside-Deficient Mice

Gangliosides are widely expressed sialylated glycosphingolipids with multifunctional properties in different cell types and organs. In the nervous system, they are highly enriched in both glial and neuronal membranes. Mice lacking complex gangliosides attributable to targeted ablation of the B4galnt...

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Main Authors: Yao, Denggao, McGonigal, Rhona, Barrie, Jennifer A., Cappell, Joanna, Cunningham, Madeleine E., Meehan, Gavin R., Fewou, Simon N., Edgar, Julia M., Rowan, Edward, Ohmi, Yuhsuke, Furukawa, Keiko, Furukawa, Koichi, Brophy, Peter J., Willison, Hugh J.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2014
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891965/
https://ncbi.nlm.nih.gov/pubmed/24431446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3996-13.2014
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