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Prenatal Dexamethasone, as Used in Preterm Labor, Worsens the Impact of Postnatal Chlorpyrifos Exposure on Serotonergic Pathways

This study explores how glucocorticoids sensitize the developing brain to the organophosphate pesticide, chlorpyrifos. Pregnant rats received a standard therapeutic dose (0.2 mg/kg) of dexamethasone on gestational days 17–19; pups were given subtoxic doses of chlorpyrifos on postnatal days 1–4, (1 m...

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Detalhes bibliográficos
Main Authors: Slotkin, Theodore A., Card, Jennifer, Seidler, Frederic J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891922/
https://ncbi.nlm.nih.gov/pubmed/24280657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2013.10.014
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